8 November 2016

The latest research publications from QBI scientists.


October 2016

Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Renteria ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivieres S, et al. (2016) Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience doi: 10.1038/nn.4398 [ePub ahead of print].

Atay C, Ryan SJ & Lewis FM (2016) "Trying to get a grip": Language competence and self-reported satisfaction with social relationships three decades post-childhood traumatic brain injury. Journal of Head Trauma Rehabilitation 31: E30-E40.

Barker RN, Hayward KS, Carson RG, Lloyd D & Brauer S (2016). Smart arm training in subacute stroke survivors with severe arm disability: A randomised controlled trial. Paper presented at the Asia Pacific Stroke Conference 14-17 July, Brisbane Convention and Exhibition Centre

Batterham PJ, McGrath J, McGorry PD, Kay-Lambkin FJ, Hickie IB & Christensen H (2016) NHMRC funding of mental health research: A case for better alignment of research funding with burden of disease. Medical Journal of Australia 205: 348-349.

Biggins PJC, Brennan FH, Taylor SM, Woodruff TM & Ruitenberg MJ (2016). Investigating the role of complement component C5a receptor 2 (C5aR2/C5L2) in spinal cord injury. Paper presented at the XXVI International Complement Workshop 4-8 September, Kanazawa City, Japan.

Byrne E & Agerbo E (2016). Sleep disorders and risk of incident depression: A population case-control study. Paper presented at the 28th ASM of Australasian Sleep Association and Australasian Sleep Technologists Association, 20-22 October, Adelaide Convention Centre.

Byrne E, Gehrman PR, Tiemeier H & Pack AI (2016). Genetic correlation analysis suggests association between increased self-reported sleep duration in adults and schizophrenia and type-2 diabetes. Paper presented at the 28th ASM of Australasian Sleep Association and Australasian Sleep Technologists Association, 20-22 October, Adelaide Convention Centre. 

Byrne EM, Gehrman PR, Trzaskowski M, Tiemeier H & Pack AI (2016) Genetic correlation analysis suggests association between increased self-reported sleep duration in adults and schizophrenia and type 2 diabetes. Sleep 39: 1853-1857.

Champ CM, Vorobyev M & Marshall NJ (2016) Colour thresholds in a coral reef fish. Royal Society Open Science 3: 160399.

Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai PC, Roetker NS, Just AC, Demerath EW, Guan W, et al. (2016) DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging 8: 1844- 1865.

Cheung A (2016) Probabilistic learning by rodent grid cells. PLoS Computational Biology 12: e1005165.

Codd L, Blackmore D, Vukovic J & Bartlett P (2016). Exercise improves learning and increases neurogenesis after an endothelin-1-induced hippocampal stroke in adult mouse. Paper presented at the Asia Pacific Stroke Conference 14-17 July, Brisbane Convention and Exhibition Centre.

Gobius I, Morcom L, Suárez R, Bunt J, Bukshpun P, Reardon W, Dobyns William B, Rubenstein John LR, Barkovich AJ, Sherr Elliott H, et al. (2016) Astroglial-mediated remodeling of the interhemispheric midline is required for the formation of the corpus callosum. Cell Reports 17: 735-747.

Golakani MH, Mohammad M, Li H, Saxena M, Breit S, Ruitenberg M & Brown D (2016). Dynamics of inflammatory immune response in a mouse model of traumatic spinal cord injury, potential therapeutic targets. Paper presented at the International Congress of Immunology 21-26 August, Melbourne Convention and Exhibition Centre.

Guadalupe T, Mathias SR, vanErp TGM, Whelan CD, Zwiers MP, Abe Y, Abramovic L, Agartz I, Andreassen OA, Arias- Vásquez A, et al. (2016) Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex. Brain Imaging and Behavior doi: 10.1007/s11682-016-9629-z [ePub ahead of print].

Hatch RJ, Leinenga G & Götz J (2016) Scanning ultrasound (sus) causes no changes to neuronal excitability and prevents age-related reductions in hippocampal CA1 dendritic structure in wild-type mice. PLoS ONE 11: e0164278.

Joensuu M, Padmanabhan P, Durisic N, Bademosi ATDs, Cooper-Williams E, Morrow IC, Harper CB, Jung W, Parton RG, Goodhill GJ, et al. (2016) Subdiffractional tracking of internalized molecules reveals heterogeneous motion states of synaptic vesicles. The Journal of Cell Biology 215: 277-292.

Lee HJ, Lee MY, Cho KC, An JY, Ha TH, Cristino AS, Kim KP & Ha K (2016, Jun). Integrated systems analysis of serum proteome profiles of individual drug responses in MDD patients. Paper presented at the 30th CINP World Congress of Neuropsychopharmacology, COEX Seoul.

Lee PH, Baker JT, Holmes AJ, Jahanshad N, Ge T, Jung JY, Cruz Y, Manoach DS, Hibar DP, Faskowitz J, et al. (2016) Partitioning heritability analysis reveals a shared genetic basis of brain anatomy and schizophrenia. Molecular Psychiatry doi: 10.1038/mp.2016.164 [ePub ahead of print].

Liang P, Fleming J, Gustafsson L & Liddle J (2016) Occupational experience of caregiving during driving disruption following an acquired brain injury. British Journal of Occupational Therapy doi: 10.1177/0308022616668359 [ePub ahead of print].

Mack JM, Schamne MG, Sampaio TB, Pertile RAN, Fernandes PACM, Markus RP & Prediger RD (2016) Melatoninergic system in Parkinson's disease: From neuroprotection to the management of motor and nonmotor symptoms. Oxidative Medicine and Cellular Longevity doi: 10.1155/2016/3472032 [ePub ahead of print]: 3472032.

Martin AK, Dzafic I, Robinson GA, Reutens D & Mowry B (2016) Mentalizing in schizophrenia: a multivariate functional MRI study. Neuropsychologia doi: 10.1016/j.neuropsychologia.2016.10.013 [Accepted manuscript].

Peyrot WJ, Robinson MR, Penninx BW & Wray NR (2016) Exploring boundaries for the genetic consequences of assortative mating for psychiatric traits. JAMA Psychiatry doi: 10.1001/jamapsychiatry.2016.2566 [ePub ahead of print].

Roelfsema C, Thurstan R, Beger M, Dudgeon C, Loder J, Kovacs E, Gallo M, Flower J, Gomez Cabrera Kl, Ortiz J, et al. (2016) A citizen science approach: A detailed ecological assessment of subtropical reefs at Point Lookout, Australia. PLoS ONE 11: e0163407.

Schiffner I, Denzau S, Gehring D & Wiltschko R (2016) Mathematical analysis of the homing flights of pigeons based on GPS tracks. Journal of Comparative Physiology A doi: 10.1007/s00359-016-1127-7 [ePub ahead of print].

Simpson EE, Marshall NJ & Cheney KL (2016) Coral reef fish perceive lightness illusions. Scientific Reports 6: 35335.

Smith CA, Sun C, Pezic A, Rodda C, Cameron F, Allen K, Craig ME, Carlin J, Dwyer T, Lucas RM, et al. (2017) Determinants of neonatal vitamin D levels as measured on neonatal dried blood spot samples. Neonatology 111: 153-161.

Thompson AW & Scott EK (2016) Characterisation of sensitivity and orientation tuning for visually responsive ensembles in the zebrafish tectum. Scientific Reports 6: 34887.

Wang T, Martin S, Nguyen TH, Harper CB, Gormal RS, Martínez-Mármol R, Karunanithi S, Coulson EJ, Glass NR, Cooper-White JJ, et al. (2016) Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB. Nature Communications 7: 12976.

September 2016

Aldridge D, Theodoros D, Angwin A & Vogel AP (2016) Speech outcomes in Parkinson's disease after subthalamic nucleus deep brain stimulation: A systematic review. Parkinsonism & Related Disorders doi: 10.1016/j.parkreldis.2016.09.022 [Accepted manuscript]

Bakshi AZhu ZVinkhuyzen AAE, Hill WD, McRae AFVisscher PM & Yang J (2016) Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traitsScientific Reports 6: 32894.

Bartlett PF. (2016). Rejuvenating the brain: Aging with cognitive sparkle. Australian Quarterly, Oct-Dec 2016, 24-29. 

Bednark J, Reynolds J, Stafford T, Redgrave P & Franz E (2016) Action experience and action discovery in medicated individuals with Parkinson’s diseaseFrontiers in Human Neuroscience 10: 427.

Biergans SDClaudianos CReinhard J & Galizia CG (2016) DNA methylation adjusts the specificity of memories depending on the learning context and promotes relearning in honeybeesFrontiers in Molecular Neuroscience 9: 82. 

Blokland GAM, Wallace AK, Hansell NK, Thompson PM, Hickie IB, Montgomery GW, Martin NG, McMahon KL, de Zubicaray GI & Wright MJ (2016) Genome-wide association study of working memory brain activation. International Journal of Psychophysiology doi: 10.1016/j.ijpsycho.2016.09.010 [Accepted manuscript].

Chung WS & Marshall NJ (2016) Comparative visual ecology of cephalopods from different habitatsProceedings of the Royal Society B: Biological Sciences 283: 20161346.

Clairfeuille T, Mas C, Chan AS, Yang Z, Tello-Lafoz M, Chandra M, Widagdo J, Kerr MC, Paul B, Merida I, et al. (2016) A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complexNature Structural and Molecular Biology doi: 10.1038/nsmb.3290 [In press].

Cocchi LSale MV, L.L. G, Bell PT, Nguyen VT, Zalesky A, Breakspear M & Mattingley JB (2016) A hierarchy of timescales explains distinct effects of local inhibition of primary visual cortex and frontal eye fieldseLife 5: 15252.

Denham R, McGee TR, Eriksson L, McGrath J, Norman R, Sawyer M & Scott J (2016) Frequent peer problems in Australian children and adolescents. Journal of Aggression, Conflict and Peace Research 8: 162-173.

Dissel S, Klose M, Donlea J, Cao L, English D, Winsky-Sommerer R, van Swinderen B & Shaw PJ (2016) Enhanced sleep reverses memory deficits and underlying pathology in Drosophila models of Alzheimer's diseaseNeurobiology of Sleep and Circadian Rhythms doi: 10.1016/j.nbscr.2016.09.001 [Accepted manuscript].

Ellis EM, Gauvain G, Sivyer B & Murphy GJ (2016) Shared and distinct retinal input to the mouse superior colliculus and dorsal lateral geniculate nucleus. Journal of Neurophysiology 116: 602-610.

Fejzo MS, Myhre R, Colodro-Conde L, Macgibbon K, Sinsheimer JS, Reddy MVPL, Pajukanta P, Nyholt DR, Wright MJ, Martin NG, et al. Hyperemesis gravidarum associated with RYR2 genetic analysis of hyperemesis gravidarum reveals association with intracellular calcium release channel (RYR2). Molecular and Cellular Endocrinology doi: 10.1016/j.mce.2016.09.017 [Accepted manuscript].

Gagnon YL, Wilby D & Temple SE (2016) Losing focus: how lens position and viewing angle affect the function of multifocal lenses in fishesJournal of the Optical Society of America A, Optics, Image Science, and Vision 33: 1901- 1909.

Gillies RM, Carroll A, Cunnington R, Rafter M, Palghat K, Bednark J & Bourgeois A (2016) Multimodal representations during an inquiry problem-solving activity in a Year 6 science class: A case study investigating cooperation, physiological arousal and belief states. Australian Journal of Education 60: 111-127.

Islam RKeramidas AXu LDurisic NSah P & Lynch JW (2016) Ivermectin-activated, cation-permeable glycine receptors for the chemogenetic control of neuronal excitation. ACS Chemical Neuroscience doi: 10.1021/acschemneuro.6b00168 [Accepted manuscript].

Joehanes R, Just AC, Marioni RE, Pilling LC, Reynolds LM, Mandaviya PR, Guan W, Xu T, Elks CE, Aslibekyan S, et al. (2016) Epigenetic signatures of cigarette smoking. Circulation: Cardiovascular Genetics doi: 10.1161/circgenetics.116.001506 [Accepted manuscript].

Kasula RChai YJBademosi ATHarper CBGormal RSMorrow IC, Hosy E, Collins BM, Choquet D, Papadopulos A, et al. (2016) The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming. The Journal of Cell Biology doi: 10.1083/jcb.201508118 [In press]. 

Li R, Steyn FJ, Stout MB, Lee K, Cully TR, Calderon JC & Ngo ST (2016) Development of a high-throughput method for real-time assessment of cellular metabolism in intact long skeletal muscle fibre bundles. Journal of Physiololgy doi: 10.1113/jp272988 [Accepted manuscript].

Matveeva OV, Nechipurenko YD, Riabenko E, Ragan C, Nazipova NN, Ogurtsov AY & Shabalina SA (2016) Optimization of signal-to-noise ratio for efficient microarray probe designBioinformatics 32: i552-i558.

Nainar S, Marshall PR, Tyler CR, Spitale RC & Bredy TW (2016) Evolving insights into RNA modifications and their functional diversity in the brain. Nature Neuroscience 19: 1292-1298.

Nguyen HG, Lloyd Jones LR & McLachlan GJ (2016) A universal approximation theorem for mixture-of-experts models. Neural Computation 28: 1-9.

Pankratz N, Schick UM, Zhou Y, Zhou W, Ahluwalia TS, Allende ML, Auer PL, Bork-Jensen J, Brody JA, Chen MH, et al. (2016) Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits. Nature Genetics 48: 867-876.

Perkes IE, Curtis J & McGrath JJ (2016) Don't ignore the skeleton in the psychiatric closet. Australian and New Zealand Journal of Psychiatry doi: 10.1177/0004867416667826 [In press].

Powell JE, Fung JN, Shakhbazov K, Sapkota Y, Cloonan N, Hemani G, Hillman KM, Kaufmann S, Luong HT, Bowdler L, et al. (2016) Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339Human Molecular Genetics doi: 10.1093/hmg/ddw320 [Accepted manuscript].

Rohrscheib CE, Frentiu FD, Horn E, Ritchie FK, van Swinderen B, Weible MW, II, O’Neill SL & Brownlie JC (2016) Intensity of mutualism breakdown is determined by temperature not amplification of Wolbachia genesPLoS Pathogens 12: e1005888. 

Sachdev PS, Thalamuthu A, Mather KA, Ames D, Wright MJ, Wen W, Bowden J, Lee T, Brodaty H, Crawford J, et al. (2016) White matter hyperintensities are under strong genetic influence. Stroke 47: 1422-1428.

Schiffner IPerez T & Srinivasan MV (2016) Strategies for pre-emptive mid-air collision avoidance in budgerigarsPLoS ONE 11: e0162435.

Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, et al. (2016) Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nature Genetics doi: 10.1038/ng.3654 [In press].

van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, Wang X, Mateo Leach I, Eijgelsheim M, Sotoodehnia N, et al. (2016) 52 genetic loci influencing myocardial mass. Journal of the American College of Cardiology 68: 1435-1448.

Visscher PM & Wray NR (2015) Concepts and misconceptions about the polygenic additive model applied to disease. Human Heredity 80: 165-170.

Wen W, Thalamuthu A, Mather KA, Zhu W, Jiang J, de Micheaux PL, Wright MJ, Ames D & Sachdev PS (2016) Distinct genetic influences on cortical and subcortical brain structuresScientific Reports 6: 32760.

Xu HM, Xu LF, Hou TT, Luo LF, Chen GB, Sun XW & Lou XY (2016) GMDR: Versatile software for detecting gene-gene and gene-environment interactions underlying complex traits. Current Genomics 17: 396-402.

Xu T, Opitz A, Craddock RC, Wright MJ, Zuo XN & Milham MP (2016) Assessing variations in areal organization for the intrinsic brain: From fingerprints to reliabilityCerebral Cortex doi: 10.1093/cercor/bhw241 [In press].

Zhang YKeramidas A & Lynch J (2016) The free zinc concentration in the synaptic cleft of artificial glycinergic synapses rises to at least 1 micromolar. Frontiers in Molecular Neuroscience 9.

Zheng F, Cui Y, Yan H, Liu B & Jiang T (2016) The effects of a genome-wide supported variant in the CACNA1C gene on cortical morphology in schizophrenia patients and healthy subjectsScientific Reports 6: 34298.