QBI offers the public the opportunity to become involved in our research, and become participants in a wide range of our human studies. Your help may be vital to solving some of humanity's greatest ailments and answering some of the biggest questions we face.

Please see a list of studies, below, that need human participants. Details such as age, and pre-existing condition requirements are specified in the listing, as well as what you would be asked to do if you are selected for the study. All studies have received Human Ethics clearances and comply with University and government policies and legislation.

If you meet the criteria and would like to be involved in a study at QBI, please contact the chief investigator listed in the study description. If you are unable to take part in a study and still wish to offer support, please consider giving to QBI.

Human study participants section

Boosting Neuroplasticity in Elderly Participants
The central nervous system is remarkably adaptive and continually changing. This study investigates using non-invasive stimulation to boost neuroplasticity.

Boosting Neuroplasticity in Elderly Participants


Boosting plasticity in elderly participants with non-invasive brain stimulation


The central nervous system is remarkably adaptive and continually changing. These neuronal changes (neuroplasticity) allow for the acquisition of new skills, the retention of memories, and even the recovery from brain injury. This study will assess whether the artificial induction of sleep-related brain activity (activity thought critical to the consolidation process) modulates the consolidation of neuroplasticity in the motor region of the brain (the motor cortex). The results from this study may provide a novel means of improving neuroplasticity induction in the elderly brain, with implications for the future rehabilitation of those recovering from brain injury (e.g., stroke).

Requirements/time commitment:

Participants will be asked to partake in two experimental sessions (with approximately one week between successive sessions). Each session will last approximately 2 hours. Within each session, participants can expect to receive transcranial magnetic stimulation, transcranial alternating current stimulation, and electroencephalography. Testing will take place at the Queensland Brain Institute (Building 79) at the University of Queensland, St Lucia. This experiment will continue to run until December 2017.

Eligibility Criteria:

  • Ages 65+ years.

  • No neurological conditions.

  • No serious head injury/loss of consciousness.

  • No implanted devices (e.g., pacemaker).

  • No personal/family history of seizure or epilepsy.

  • No neuroactive medications.


Dr Martin Sale



Corpus Callosum Dysgenesis database
In this study we aim to survey the Australian population of patients with agenesis or dysgenesis of the corpus callosum (ACC) to assess the range of disorders associated with callosal malformations in Australia.

Corpus Callosum Dysgenesis database


Agenesis/Dysgenesis of the corpus callosum database


Our aim is to collect information about adults and children who have been diagnosed with agenesis or dysgenesis of the corpus callosum (ACC). Malformations of the corpus callosum are relatively rare and most studies so far have involved smaller groups of people.

In this study we aim to survey the Australian population of ACC patients to assess the range of disorders associated with callosal malformations in Australia. If you or your child has been diagnosed with agenesis or dysgenesis of the corpus callosum we invite you to contact us and take part in this study.

Requirements/time commitment:

We are asking for your participation by filling out a questionnaire and sharing with us information about you or your child’s diagnosis, implications and family history. Any copies of documentation such as digital copies of MRI scans would be very much appreciated. No active participation in any further research is needed at this stage. You will be asked to sign a consent form that will allow us to store your or your child’s information in our database. In the questionnaire you will have the option to indicate if you wish to be informed of further studies. At any given time you have the right to retract your participation and remove your information from the database.

Eligibility criteria:

  • Individuals who have been diagnosed with malformations of the corpus callosum.


Professor Linda Richards
07 3346 6355

Optimising exercise for cognitive function

Optimising exercise for cognitive function

Exploring the effect of exercise on cognitive function in older adults

It is well known that exercise has a positive influence on cognitive function during aging. However, the optimal dose, intensity and duration of exercise for improving cognitive function is not known, nor are the mechanisms by which exercise may prevent or even reverse cognitive decline.

Join our study to help identify the ‘sweet spot’ for exercise and memory. How much is enough? How much is too little?

Are you aged 65 – 85 and do you want to:

  • become more physically active?
  • participate in regular supervised exercise?
  • learn more about you brain health, learning and memory?
  • be part of supportive community?

Healthy men and women aged 65–85 are invited to participate in a six-month supervised exercise program. To be eligible participants must have no history of stroke or brain trauma, no diagnosed mental illness or cognitive function impairment, be free of significant cardiovascular disease, have a healthy BMI (< 30 kg/m2) and be able and willing to commit to the duration of the exercise program. Participation will include fitness tests, cognitive function testing, MRI scans of the brain, and small blood samples. 

Participants will be divided into three groups to complete either low-intensity (very easy), moderate-intensity (easy) exercise or aerobic-interval (hard) exercise three times per week for six months. All exercise will be supervised and monitored and we will measure cognitive function, fitness, blood hormones, genetic factors and brain volume before beginning exercise, at regular interval during the exercise program and six months following the conclusion of the exercise program. 

Contact Information

Contact Dr Mia Schaumberg and the Healthy Brain-Ageing Team (healthybrains@uq.edu.au) for further details.

The Healthy Brain-Ageing Team
The Stafford Fox Exercise and Healthy Brain-Ageing Centre
School of Human Movement and Nutrition Sciences (Building 26B)
The University of Queensland | St Lucia, QLD, 4072 | Australia  
T: +61 7 3443 3209
Email: healthybrains@uq.edu.au
Website: archive-qbi.stage.drupal.uq.edu.au/exercisestudy

About Professor Perry Bartlett